Signs and symptoms of pancreatic cancer

Signs and symptoms of pancreatic cancer

Symptoms of exocrine pancreatic cancer and tumors of neuroendocrine pancreatic (emerging) are often different, so it has been described separately.

The presence of one or more of the symptoms below does not mean that you have cancer of the pancreas. In fact, many of these symptoms are more likely to be caused by other conditions. However, if you have any of these symptoms, it is important to have them checked by a doctor so that they can find the cause and cure, if necessary.

Signs and symptoms of pancreatic cancer

Signs and symptoms of exocrine pancreatic cancer

Pancreatic cancer early often does not cause any signs or symptoms. At the time that does cause symptoms, they often spread beyond the pancreas.

Jaundice and symptoms related

Jaundice is a yellowing of the eyes and skin. Most people with pancreatic cancer (and almost all people with cancer Empoli) will be one of the first symptoms of jaundice.

Jaundice occurs due to the accumulation of bilirubin, a yellow color dark brown substance made in the liver. Normally, the liver secretes bilirubin as part of a liquid called bile. The yellow passes through the common bile duct into the intestine, where it helps to get rid of the fat. Eventually leaves the body in the stool. When the common bile duct becomes blocked, bile can not reach into the intestines, and the level of bilirubin in the body accumulate.

Cancers that begin in the head of the pancreas and near the common bile duct. These cancers Press the channel and cause jaundice while they are still relatively small, and that can sometimes lead to these tumors that are found at an early stage. But cancers that start in the body or tail of the pancreas do not press on the channel until it has spread through the pancreas. By that time, the cancer is often spread beyond the pancreas as well.

When it is spreading pancreatic cancer, and often goes to the liver. This can also lead to jaundice.

Dark urine: Sometimes, the first sign of jaundice is darker urine. As bilirubin levels in the blood increase, the urine becomes brown in color.

Light-colored stools, or greasy: bilirubin usually helps give stool color brown. If the prohibition of the bile duct, it may be pale or gray stools. Also, if the bile and pancreatic enzymes can not get through to the intestines to help break down fats, it can become greasy stools were floating in the toilet.

Itchy skin: When bilirubin builds up in the skin, and can begin to itch, as well as turning yellow.

Pancreatic cancer is not the most common reason for jaundice. Other reasons, such as gallstones, hepatitis and other liver and biliary tract disease, is more common.

Abdominal or back pain

Pain in the abdomen (belly) or back is common in pancreatic cancer. Cancers that start in the body or tail of the pancreas can grow to a large extent and starts to put pressure on other nearby organs, causing pain. Cancer has also spread to the nerves surrounding the pancreas, which often cause back pain. Of course, pain in the abdomen or back is common to some extent and often cause other than cancer of the pancreas.

Weight lose and loss of appetite

Unintended weight loss is very common in people who suffer from pancreatic cancer. It is often these people are few or no appetite.

Vomiting and nausea

If cancer presses at the far end of the stomach and can block the part, making it difficult for the food to get through. This can cause nausea, vomiting, and pain, which tend to be worse after eating.

Gallbladder or liver enlargement

If it blocks the bile duct cancer, it can accumulate in the gallbladder bile, making it the largest. Sometimes a doctor can feel this (a large swelling under the right rib cage) during the physical examination. It can also be seen on imaging tests.

Pancreatic cancer also can sometimes enlarge the liver, especially if cancer has spread to the liver. Your doctor may be able to feel this right under the rib cage, as well as on the exam, or can be seen on imaging tests.

Blood clots

Sometimes, the first evidence that a person is suffering from pancreatic cancer is a blood clot in a large vein, often in the leg. This is called deep vein thrombosis or DVT. Symptoms may include pain, swelling, redness, and warmth in the affected leg. Sometimes a piece of the clot can go and travel to the lungs, which may make it difficult to breathe or cause chest pain. It called a blood clot in the lungs and pulmonary embolism, or PE.

Still, the presence of clots in the blood does not usually mean that you have cancer. Most are caused by blood clots by other things.

Adipose tissue abnormalities

Some people with pancreatic cancer develops uneven texture of the fatty tissue under the skin. This is caused by the release of pancreatic enzymes that digest fat.

diabetic

Rarely, pancreatic cancer causes diabetes (high blood sugar) because it destroys the insulin-making cells. Symptoms may include the thirst, hunger, and the need to urinate frequently. Often, it can lead to minor changes in blood sugar levels that do not cause symptoms of diabetes and cancer, but can still be detected with blood tests.

Signs and symptoms of tumors of neuroendocrine pancreatic

Neuroendocrine tumors of the pancreas (emerging) often release of excess hormones in the bloodstream. Different types of tumors make various hormones, which can lead to different symptoms.

Gastrinoma

These tumors make gastrin, a hormone that tells the stomach to make more acid. Cause a lot of gastrin condition known as Zollinger-Ellison, who makes a lot stomach acid syndrome. This leads to stomach ulcers, which can cause pain, nausea, and loss of appetite. Can acute ulcer starts bleed? If bleeding severe it can lead to anemia (too few red blood cells), which can cause symptoms such as feeling tired and being short of breath. If the bleeding more severe, it can make the stool black or dark. Bleeding can be the same life-threatening.

If you arrived in the stomach and intestinal acid minute, it can lead to damage to the intestinal lining cells, break down digestive enzymes before they have a chance to digest the food. This can cause diarrhea and weight loss.

Glucagonomas

These tumors make glucagon, a hormone that increases the glucose (sugar) levels in the blood. Most of the symptoms that can be caused by glucagonoma are mild and most often caused by something else.

Glucagon excess can raise blood sugar in the blood, which sometimes leads to diabetes. This can cause symptoms such as thirst and hunger, and the need to urinate frequently.

People with these tumors also have problems with diarrhea, weight loss, and malnutrition. Feeding problems can lead to symptoms such as irritation of the tongue (tongue) and the corners of the mouth (angular cheilitis).

Symptoms that brings most people with glucagonoma to the doctor is a skin rash called erythema migratory necrolytic. This is a red rash with swelling and blisters that often travels from place to place on the skin.

Insulinoma

These tumors make insulin, which reduces sugar levels in the blood. A lot of insulin leads to low blood sugar (hypoglycemia), which can cause symptoms such as weakness, confusion, sweating, rapid heartbeat. When it gets to the blood sugar is too low, it can lead to any person who passes or even goes into a coma and having seizures.

Somatostatinomas

These tumors make somatostatin, which helps regulate other hormones. The symptoms of this type of tumor can include abdominal pain, nausea, loss of appetite, weight loss, diarrhea, and symptoms of diabetes (thirst, hunger, and the need to urinate frequently), jaundice (yellowing of the skin and eyes).

Early symptoms tend to tumor Sumaatostatena to be mild and most often caused by other things, so these tumors are often diagnosed at an advanced stage. Often, it is not found even spread to the liver, and when they cause problems such as jaundice and pain.

VIPomas

These tumors make a substance called vasoactive intestinal peptide (VIP). Also, a lot of Vips can lead to problems with diarrhea. This may be mild at first, but it gets worse with time. At the time, they are diagnosed, and most people have severe diarrhea.

They can Other symptoms include nausea, vomiting, muscle cramps, and a feeling of weakness or fatigue, and facial flushing (warmth and redness of the face or neck).

People with these tumors also tend to have low levels of acid in their stomachs, which can lead to problems with digesting food.

PPomas

These tumors make pancreatic polypeptide (PP), which helps regulate both the secretions of the pancreas and the endocrine glands. It can cause problems such as abdominal pain, enlarged liver. Some patients also get watery diarrhea.

Cancerous tumors

These tumors often make or serotonin precursor, 5-HTP. When making these materials pancreatic tumor, for the first time to travel to the liver. The liver breaks down these materials before they can access the rest of the body and cause problems. Because of this, and cancerous tumors often do not cause symptoms until spreading beyond the pancreas.

When doing these tumors spread, it is often to the liver. There, the cancer cells can release hormones directly into the blood which leaves the liver. This can cause carcinoid syndrome, with symptoms including cleaning (redness and warmth in the face or neck), diarrhea, breathing, and rapid heart rate. Often these symptoms occur in episodes, between which the person may feel fine.

Over a long period of time, it can be hormone-like substances from these tumors damage to the heart valves, causing shortness of breath, weakness, a hole in the heart (the sound is natural for the heart).

Neuroendocrine tumors are working

These tumors do not make excess hormones, so as not to cause symptoms in the early stages, and often grow quite large before it is found. Most of these cancers and begin to cause problems as they get larger or spread beyond the pancreas. Symptoms can be like those of exocrine pancreatic cancer, including jaundice (yellowing of the eyes and skin), and abdominal pain, and weight loss.

Symptoms caused by the spread of cancer

When the spread of emerging pancreas, and often they go to the liver. This can be seen in the liver, which can cause pain and loss of appetite. It also can affect the function of the liver, which sometimes leads to jaundice (yellowing of the skin and eyes), and laboratory tests are abnormal.

These cancers can also spread to other organs and tissues. Symptoms depend on where the cancer is growing. For example, cancer spreads to the lungs can cause shortness of breath or coughing. The proliferation of the bone can cause pain in the bones.

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